Telemedicine & telehealth

Telemedicine and telehealth covers the platforms delivering remote clinical care - synchronous video visits, asynchronous messaging consultations, virtual specialist networks, and the DTC prescription channels that grew up alongside them. The category exploded through COVID, with US virtual visit volume rising more than 60x at peak. Most of that volume reverted by 2023, leaving a much smaller core business that is still material in mental health, chronic disease management and a handful of DTC prescription categories. Public-market telehealth equity has been brutal - Teladoc traded above $300 in 2021 and below $10 by 2024; Babylon Health went bankrupt in 2023; Cerebral has been the subject of DOJ investigations over controlled-substance prescribing. The structural survivors are DTC consumer telehealth (Hims & Hers, Ro) and B2B virtual care plumbing.

The sector spans general virtual primary and urgent care, DTC consumer telehealth and prescription, virtual mental health, virtual specialty and chronic disease care, asynchronous and on-demand provider networks, and the B2B telehealth infrastructure used by hospitals and health plans.

Revenue comes from per-visit fees paid by patients or insurers, monthly subscription pricing on DTC consumer telehealth, PMPM contracts with employers and health plans, B2B SaaS sold to hospital and provider systems, and pharmacy revenue from prescribed medications dispensed through owned or partner pharmacies.

Telemedicine & telehealth is part of Digital health.

$123B

Global market size

32

Public companies

Y Combinator
Andreessen Horowitz
General Catalyst
Alumni Ventures

Key VC investors

Fabric
CoachCare
Hims & Hers
LXE Hearing

Key strategic buyers

Business model

How telemedicine & telehealth companies monetize?

Telemedicine and telehealth companies monetize through DTC subscription and prescription, PMPM employer contracts and pharmacy revenue.

PMPM employer & health plan contracts

Per-member-per-month fees paid by self-insured employers and health plans for access. The historical Teladoc model; the model under most pressure as employer wallets consolidate.

DTC subscription & prescription

Monthly subscription plus per-prescription pricing paid directly by consumers. The Hims & Hers and Ro engine; the structurally strongest model in the category.

Per-visit fee-for-service

Per-visit billing to insurers under fee-for-service codes. Common at general virtual urgent care and specialist consult networks.

Virtual specialist networks

Curated specialist consult networks selling into health plans, employers and self-pay channels. The Doximity and Included Health model.

B2B virtual care infrastructure

Video, scheduling and clinical workflow software sold to hospitals and health systems. Amwell and Caregility lead the white-label side.

Pharmacy revenue

Take rate on prescription fulfilment through owned or partner pharmacies, often the highest-margin line in DTC telehealth. Hims, Ro and Lemonaid all rely on this layer.

Telemedicine & telehealth valuations in May 2026

Public telemedicine & telehealth comps trade at 2.0x EV/Revenue. Median revenue multiple across telemedicine & telehealth M&A deals was 2.3x in the last 12 months. Median revenue multiple across telemedicine & telehealth VC rounds was 12x in the last 12 months.

2.0x

Median EV/Revenue as of May 2026 for public telemedicine & telehealth companies

13x

Max Healthcare Institute

Max Healthcare Institute is the highest valued public telemedicine & telehealth company based on EV/Revenue (excluding outliers)

2.3x

Median EV/Revenue across telemedicine & telehealth M&A deals in the last 12 months

12x

Median EV/Revenue across telemedicine & telehealth VC rounds in the last 12 months

Sector breakdown

Telemedicine & telehealth market segments

Telemedicine and telehealth spans DTC consumer telehealth, virtual mental health and B2B virtual care infrastructure.

DTC consumer telehealth

Direct-to-consumer brands offering virtual visits and recurring prescriptions for sexual health, hair, skin, mental health, weight loss and other categories. Key players: Hims & Hers (NYSE: HIMS), Ro, Lemonaid Health (23andMe) and Wisp.

General virtual primary & urgent care

On-demand video visits for routine primary and urgent care, sold mainly through health plans and employer benefits. Key players: Teladoc Health, Amwell, Doctor on Demand (Included Health) and MDLive (Cigna Evernorth).

Virtual mental health

Video and asynchronous mental health visits, often paired with medication management. Subject to ongoing DEA controlled-substance rule changes. Key players: Talkspace (NASDAQ: TALK), BetterHelp (Teladoc), Cerebral and Brightside Health.

Virtual specialty & chronic disease care

Specialty consults and longitudinal chronic disease management delivered virtually - cardiology, dermatology, behavioural health, weight management. Key players: Included Health, Firefly Health, Hello Heart and Vida Health.

B2B virtual care infrastructure

Video, scheduling and clinical workflow platforms sold to hospitals and health plans for white-label virtual care. Key players: Amwell (NYSE: AMWL), Caregility, Bluestream Health (Vocera/Stryker) and Zoom for Healthcare.

Physician network platforms

Physician-facing networks combining communication, referrals and telehealth. Key players: Doximity (NYSE: DOCS), Sermo, Figure 1 and Medscape (WebMD).

International telehealth platforms

European and global virtual care companies, generally with stronger payer integration than US DTC. Key players: KRY/Livi (Sweden), Babylon Health (defunct 2023), Push Doctor and Doctorlib.

Fractional CFO, financial modelling and deal advice for telemedicine & telehealth companies

See how Flow helps telemedicine & telehealth founders.

We speak founders' language and have great operational understanding of telemedicine & telehealth businesses.

Book an intro call - we'll look under the hood and recommend concrete next steps.

Explore pricing
Sector KPIs

Key telemedicine & telehealth KPIs to track

Members or subscribers, visits per quarter, ARPU per visit and CAC payback are the metrics investors track in telemedicine and telehealth.

KPIDefinition
Members or subscribersCovered or subscribed lives. DTC and PMPM businesses report this differently - Hims subscribers (annualised paying customers) vs Teladoc covered lives.
Visits per quarterSynchronous or asynchronous visits delivered. The activity metric for general virtual urgent care and B2B platforms.
ARPU / revenue per visitAverage revenue per active subscriber or per visit. The subscription-attach ARPU is the watched figure at Hims and Ro.
Net revenue retentionExisting-customer revenue 12 months later. Strong DTC telehealth shows 110%+ NRR through upsell into new prescription categories.
PMPMPer-member-per-month price for B2B contracts. Decision-relevant when comparing Teladoc, Amwell and Included Health employer contracts.
Gross marginDTC telehealth gross margin sits at 70-80% on the service side; the pharmacy side has compressed materially as Hims and Ro fulfil more of their own prescriptions.
CAC paybackTime to recover customer acquisition cost. Material at DTC players given heavy paid marketing spend; the unit-economics input separating sustainable from unprofitable players.
Prescription volumeAnnual prescriptions filled through the platform's pharmacy partners. The activity metric that maps DTC telehealth scale to commercial impact for pharma.
Key players

Main telemedicine & telehealth players globally

The most active telemedicine and telehealth companies and category leaders globally.

CompanyHQOverview
Hims & Hers Health
hims.com
San Francisco
DTC telehealth platform across men's and women's sexual, hair, skin, mental health and weight categories (NYSE: HIMS). One of the few digital health public stories well above its IPO price; rolled out compounded GLP-1 offering in 2024.
Teladoc Health
teladochealth.com
Purchase
Largest publicly traded virtual care platform (NYSE: TDOC). Includes BetterHelp (consumer mental health) and Livongo (chronic care). Multiple write-downs since the 2021 peak; new CEO Chuck Divita in mid-2024.
Boston
B2B virtual care infrastructure (NYSE: AMWL) sold to hospital systems and health plans. Anchored by the Converge platform; serves large clients including CVS Health and the Veterans Health Administration.
Doximity
doximity.com
San Francisco
Largest US physician professional network and telehealth platform (NYSE: DOCS). Roughly 80% of US physicians on the platform; high-margin advertising, recruiting and telehealth subscriptions.
New York
DTC telehealth platform across men's health, women's health (Modern Fertility), weight management and dermatology. Last valued at $7B in 2022; private and reportedly profit-focused since 2023 cost-out programs.
Talkspace
talkspace.com
New York
Listed virtual mental health platform (NASDAQ: TALK) covering DTC and payer-reimbursed therapy. Made the strategic pivot from DTC to insurance reimbursement in 2022-23 and returned to profitability.
Cerebral
cerebral.com
San Francisco
Virtual mental health platform that grew rapidly during COVID. Faced DOJ scrutiny over controlled-substance prescribing in 2022; reorganised, sharply reduced staffing, and is now operating at smaller scale under new leadership.
Lemonaid Health
lemonaidhealth.com
San Francisco
Virtual care and telepharmacy platform acquired by 23andMe in 2021 for $400M. Continued under 23andMe ownership through the 2025 bankruptcy and Regeneron acquisition.
Included Health
includedhealth.com
San Francisco
Virtual primary care, specialist consults, navigation and behavioural health sold to self-insured employers and health plans. Formed in 2021 from the Grand Rounds + Doctor on Demand merger; majority backed by Carlyle.
KRY/Livi
livi.co.uk
Stockholm
Largest European telehealth platform, operating in the UK, France, Germany and Nordics. Backed by Index Ventures and Accel; majority-funded by national health-service contracts rather than DTC consumer subscriptions.

Board pack needs work?

Investor-grade reporting from a fractional CFO who's sat on both sides of the table.

Market trends

Key telemedicine & telehealth market trends

GLP-1s reshaping DTC telehealth, DEA controlled-substance rules and pharmacy vertical integration are reshaping telemedicine and telehealth right now.

GLP-1s reshaping DTC telehealth

Hims & Hers, Ro and Eden launched compounded semaglutide offerings through 2024 and pulled in hundreds of millions in revenue. The FDA's October 2024 decision ending the shortage status for semaglutide reset which players can continue compounding; Hims's response (continuing in personalised compounded form) is the most-watched commercial outcome of the year.

DEA controlled-substance telehealth rules

The DEA's ongoing rulemaking on remote prescribing of controlled substances (most recently extended through end-2025) is the binding constraint on virtual ADHD and addiction treatment economics. Cerebral, Done, Wisdo and Bicycle Health have all reorganised around this regulatory framework.

Babylon Health collapse and B2B telehealth retrenchment

Babylon Health filed for administration in August 2023, ending a $4.2B SPAC story. The unwinding closed the chapter on a wave of B2B platform telehealth bets and reset valuations for B2B providers like Amwell and 98point6.

Pharmacy vertical integration in DTC telehealth

Hims & Hers acquired MedisourceRx in 2023 and Ro built compounding capacity through 2024; both moves restructure the gross-margin profile of DTC telehealth. Pharmacy-owned models now run 20+ points of gross-margin advantage over partner-fulfilled.

Employer telehealth wallet consolidation

Self-insured employers have aggressively consolidated point solutions through Transcarent, Included Health and Quantum Health since 2023. Standalone telehealth vendors are being bundled or dropped, and PMPM pricing has compressed.

Ambient and AI scribe integration

Virtual care platforms have integrated ambient AI scribes (Abridge, Suki, DAX) and triage agents into the live visit workflow through 2024-25. The result is shorter visits and lower clinician cost; Teladoc, Included Health and Amwell all shipped material AI features in 2024-25.

Similar verticals to telemedicine & telehealth

Explore niches like digital therapeutics, EHR & practice management, fitness & wellness and health data & analytics.

Explore other sectors

We know tech inside & out.

We live and breath tech - true understanding of how startups operate is fundamental at what we do.

SoftwareAI & MLFintechConsumer internetDigital mediaE-commerce & marketplacesConsumer productsMobilityDigital healthIndustrial technologyDigital infrastructureIT services

Recent insights across telemedicine & telehealth and beyond

Talk to us

Schedule a call to get a health check on your business and see how we could help.

Fractional CFO

Stages

Countries

Cities

Sectors

© 2026 Flow Partners (London) Ltd. All rights reserved. Registered as a limited liability company in England and Wales (registered number 12969521).